An inside-out vein graft filled with platelet-rich plasma for repair of a short sciatic nerve defect in rats

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Inside-out and standard vein grafts associated with platelet-rich plasma (PRP) in sciatic nerve repair. A histomorphometric study.

Purpose: To evaluated the tubulization technique with standard and inside-out vein, filled or not with platelet-rich plasma (PRP), in sciatic nerve repair. Methods: Seventy male Wistar rats were randomly divided into five groups: IOVNF (Inside-Out Vein with No Filling); IOVPRP (Inside-Out Vein filled with PRP); SVNF (Standard Vein with No Filling); SVPRP (Standard Vein filled with PRP); Sham ...

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Functional, Histomorphometrical and Immunohistochemical Assessment of Sciatic Nerve Regeneration through Inside-Out Vein Graft in Rat

Objective- Comprehensive functional, histomorphometrical and immunohistochemical assessment of sciatic nerve regeneration through an inside-out vein graft in rat. Design- Experimental in vivo study. Animals- Fifty- four healthy male White Albino rats. Procedures- The rats were divided into three experimental groups (n=18), randomly: Sham-operation (NC), Transected control (TC) and Inside-out ve...

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Functional recovery of sciatic nerve through inside-out vein graft in rats.

OBJECTIVE Present study aimed at further comprehensive functional, histomorphometrical and immunohistochemical assessment of peripheral nerve regeneration using rat sciatic nerve transection model. METHODS The 10-mm rat sciatic nerve gap was created in rats. In control group nerve stumps were sutured to adjacent muscle and in treatment group the gap was bridged using an inside-out vein graft....

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Inside-out vs. standard vein graft to repair a sensory nerve in rats.

Nerve regeneration in a sensory nerve was obtained by the application of different techniques: inside-out vein graft (IOVG group) and standard vein graft (SVG group). These techniques provide a good microenvironment for axon regeneration in motor nerves, but their efficiency for regeneration of sensory nerves is controversial. The saphenous nervtce was sectioned and repaired by the inside-out a...

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Comparative study between standard and inside-out vein graft techniques on sciatic nerve repair of rats. Muscular and functional analysis.

Purpose: To compare the functional result of standart vein grafts and inside-out vein graft technique on sciatic nerve repair. Methods: We used 24 male Wistar rats divided into 4 groups: control group (CG), standard vein graft group (SVG), Inside-out vein graft group (IOVG) and denervated Group (DG). SVG, IOVG and DG underwent total section of the sciatic nerve, SVG and IOVG however underwent...

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ژورنال

عنوان ژورنال: Neural Regeneration Research

سال: 2014

ISSN: 1673-5374

DOI: 10.4103/1673-5374.137587